The latest Toxic Substances Control Act (TSCA) Chemical Substance Inventory is now available on EPA’s website. The TSCA Inventory is a list of all existing chemical substances manufactured, processed or imported in the U.S.

This update to the public TSCA Inventory is part of EPA’s biannual posting of non-confidential Inventory data. The next regular update of the TSCA Inventory is planned for summer 2023.

The TSCA Inventory contains 86,685 chemicals, of which 42,170 are active in U.S. commerce. Other updates to the Inventory include new commercial activity data, unique identifier data and regulatory flags (e.g., significant new use rules and test orders).

Additionally, several hundred substances are now listed with their specific chemical identities after having been moved from the confidential portion of the Inventory to the public portion as part of EPA’s ongoing TSCA confidential business information (CBI) review efforts.

Lastly, TSCA submitters are reminded to regularly check for any correspondence relating to their submissions in EPA’s Central Data Exchange (CDX). EPA sends critical and time-sensitive information regarding confidentiality claims through CDX, and failing to open this correspondence can delay the Agency’s processing of those claims. For more information, visit

Have Regulatory questions? Email us today at or call (888) 673-7776.

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